New Comedy looks at human relations, while Old Comedy satirizes the life of the polis. For this reason Old Comedy is called political comedy and bears marked similarity to modern political cartoons. New Comedy focused on family matters such as complications in love relationships. Another difference between Old Comedy and New is that the chorus is a central feature of older drama (whether tragedy or comedy).
This picture is an example scene from one of the Greeks' Old Comedies.
Old Comedy Plays:
Acharnians by Aristophanes
Clouds by AristophanesKnights by Aristophanes
New Comedy Plays:
Perikeiromenē by Menander
Second Adelphoe by Menander
Amphitruo by Plautus